Tillson, a former captain at Bristol Rovers, travels with the Grecians squad to take on a Pirates side who have lost just once in their previous six outings.
"I am looking forward to it," Tillson told Exeter's official website. "They've done really well recently and we have a real job to do.
"You have to beat the teams down the bottom of the league. You can't go losing to them and beating the top sides.
"It's a really good game to look forward to at this stage of the season and we have to make sure we make it hard for them.
"We will have a good following there being only an hour down the road, the atmosphere will be great and our fans were fantastic when we went up there earlier in the season."
Source: PA
Source: PA